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CareFusion case studies are based on individual hospital characteristics and do not anticipate the average result for all hospitals. Customer results will vary.
Journal Article
Childhood outcome after early high-frequency oscillatory ventilation for neonatal respiratory distress syndrome
In a previous multicenter controlled clinical trial, we randomly assigned surfactant- treated premature newborns with moderate to severe respiratory distress syndrome to early treatment with high-frequency oscillatory ventilation (HFOV) or to conventional ventilation (CV). Compared with control infants who were treated with CV, neonates who were treated with HFOV using a strategy designed to recruit and maintain lung volume and minimize oxygen exposure had clinical evidence of improved pulmonary outcome and less lung injury. We report a follow-up study designed to determine whether clinical differences persisted between these study groups.
Journal Article
Your strategy for continuous supply savings
When times are tough and cost reductions are the order of the day, C-suite leaders often look for solutions that will bring immediate results. To achieve lasting results, hospitals must both dig deeper into the supply chain and reach out to other areas to maximize savings. Given today’s cost pressures, organizations need to better understand how their supplies are being used in individual service areas and their potential for improved efficiencies.
Journal Article
Efficacy of surgical preparation solutions in foot and ankle surgery
Previous studies have demonstrated higher infection rates following orthopaedic procedures on the foot and ankle as compared with procedures involving other areas of the body. The purpose of this study was to evaluate the efficacy of three different surgical skin-preparation solutions in eliminating potential bacterial pathogens from the foot.
Journal Article
Comparison of percutaneous management techniques for recurrent malignant ascites

The PleurX subcutaneous tunneled catheter is approved for repeated, long-term drainage of malignant pleural effusions; however, there is limited literature describing its use in malignant ascites. The authors compared the safety and efficacy of two percutaneous drainage methods: large volume paracentesis and PleurX catheter placement over a 41-month period. The PleurX catheter provided effective palliation with a complication rate similar to that for large volume paracentesis, while preventing the need for frequent trips to the hospital for repeated percutaneous drainage.

J Vasc Interv Radiol. 2004 Oct;15(10):1129-31
Rosenberg S, Courtney A, Nemcek AA Jr, Omary RA.

Journal Article
Palliation of malignant ascites

The management of recurrent, symptomatic malignant ascites can be problematic for physicians and patients. The most common, low‐risk method is large‐volume paracentesis. Patient disease progression often leads to rapid reaccumulation of ascites, which requires frequent return visits to the hospital for symptom management. Other techniques have been developed to achieve palliation of symptoms, including tunneled external drainage catheters, peritoneal ports, and peritoneovenous shunts.

Rosenberg SM.
Gastroenterol Clin North Am. 2006 Mar;35(1):189‐99, xi.

Journal Article
Management of Malignant Ascites: Current Treatment Options

Overview of malignant ascites and available therapies, including the PleurX drainage catheter.

Behrendt, R
Oncology Nursing News, January 2008 2(1): 1‐16.

Journal Article
Management of malignant pleural effusions using the PleurX catheter

BACKGROUND: A malignant pleural effusion can cause significant morbidity to terminal patients. Drainage and control of the fluid can provide great palliation. Improving the quality of life for these patients on an outpatient basis is a worthy goal.

Ann Thorac Surg. 2008 Mar; 85(3):1049-55. Warren WH, Kalimi R, Khodadadian LM, Kim AW.

Journal Article
Managing recurrent pleural effusions with an indwelling pleural catheter

Review of catheters available for chest drainage and 3 cases of patients treated using a PleurX drainage catheter.

JAAPA. 2009 May; 22(5): 27-8, 33-4. Schrader JM, Ferson PF.

Journal Article
Management of symptomatic ascites in recurrent ovarian cancer patients using an intra-abdominal semi-permanent catheter

Ascites is commonly present in women with advanced-stage ovarian cancer. No standardized protocol exists for the treatment of the patient with recurrent ovarian cancer and rapidly reaccumulating malignant ascites. Palliation of symptoms is most commonly achieved through repeated paracentesis, a procedure that potentially results in injury to intra-abdominal organs, infection, and patient discomfort. Our goal was to improve patient comfort by alleviating symptoms and reducing the need for paracentesis. The PleurX catheter offers a number of potential advantages over traditional treatment modalities. Clearly, larger study numbers are required to quantify the morbidity associated with the PleurX catheter.

Iyengar TD, Herzog TJ. Am J Hosp Palliat Care. 2002 Jan-Feb;19(1):35-8.

Journal Article
Management of recurrent malignant pleural effusions with a chronic indwelling pleural catheter

Many patients with various forms of cancer develop sooner or later malignant pleural effusions, resulting in feelings of discomfort and reduced quality of life. Several palliative options exist, including repeated thoracocentesis and pleurodesis with a sclerosing agent. However, these "therapeutic" possibilities are not always successful and sometimes even contraindicated. Also, patients need to visit the hospital regularly or have to stay hospitalized for several days. A chronic indwelling pleural catheter could provide a simple, completely outpatient way to provide respiratory relief and improvement in quality of life in patients with malignant pleural effusions. We evaluated retrospectively the course of 17 patients with malignant pleural effusions who were treated with a chronic indwelling pleural catheter (PleurX).

Lung Cancer. 2005 Oct; 50(1): 123-7. van den Toorn LM, Schaap E, Surmont VF, Pouw EM, van der Rijt KC, van Klaveren RJ.